C-CLEAN Project

C-CLEAN_ES.JPG

Title:

Proof of concept for rapid detection of surfaces contaminated by SARS-CoV-2 using multispectral holographic and optical analysis with artificial intelligence.

Type: 

Collaborative project in the fight against the COVID-19 pandemic. Funded within the Emergency Call for Research Projects on SARS-CoV-2 and COVID-19 of the Institute of Health 'Carlos III' (Spanish Ministry of Science, Innovation and Universities), and a Project of Acquisition of Scientific and Technological Equipment of the Spanish Ministry of Science, Innovation and Universities, and 'ERDF A way of making Europe'.

Principal investigator:

Prof. Dr. Emilio Gómez-González (Universidad de Sevilla, Spain).

Description:

​Design and developement of a proof-of-concept of detection of SARS-CoV-2 virus deposited on surfaces through the use of optical technologies combined with Artificial Intelligence (AI). Portable prototypes that combines multispectral imaging in the optical range (from ultraviolet to infrared). thermal) and in the terahertz range, with methods of analysis using advanced statistics, neuronal networks and spectral descriptors.

Researchers from 11 institutions participate in this project:


Results of the Project include a new technique for the rapid, non-contact and reagent-free detection of viruses in fluid samples (both liquid droplets and dry residues). These results are detailed in the Dissemination and Publications sections below. The researchers keep working actively on the analysis of human samples of SARS-CoV-2.

Publications:

2022 - Gomez-Gonzalez E et al. Optical imaging spectroscopy for rapid, primary screening of SARS‑CoV‑2: a proof of concept. Scientific Reports, 2021 [Nature Publishing Group], 10.1038/s41598-022-06393-3

2021  - Gomez-Gonzalez E et al. Hyperspectral image processing for the identification and quantification of lentiviral particles in fluid samples. Scientific Reports, 2021 [Nature Publishing Group], doi:  10.1038 / s41598-021-95756-3 .

Dissemination:

Publication on NCT magazine ENG

Publication of proof-of-concept using hyperspectral imaging (February 2022) - Press release ESP ENG

Andalusian Regional Government  ESP

Publication of initial results (August 2021) - Press release  ESP  ENG

phys.org

healtheuropa.eu

Andalusian Regional Government  ESP

Project starts (April 2020) - Press release ESP

Government of Spain ESP   ENG

Institute of Health 'Carlos III' (Spanish Ministry of Science, Innovation and Universities)  ESP  ENG

HUMAINT Project of the Joint Research Centre, European Commission ENG

ELLIS European Platform  ENG

Andalusian Regional Government ESP   

Videos:

Universidad de Sevilla

See also other related publications in OPD Project.

Related Projects:

PROJECT: "Proof of concept for rapid detection of surfaces contaminated by SARS-CoV-2 using multispectral holographic and optical analysis with artificial intelligence (Project C-CLEAN)".

Program: Emergency Call for Research Projects on SARS-CoV-2 and COVID-19.

Entity: Institute of Health 'Carlos III' (Spanish Ministry of Science, Innovation and Universities).

Web:  https://sede.micinn.gob.es/stfls/eSede/Ficheros/2019/RPRD_EQC2019_f.pdf

PROJECT: "Equipment for the acquisition and integration of hyperspectral images in the optical, thermal, terahertz (THz) and X-ray ranges in Laboratory and Field environments"

Program: State Subprogram for Research Infrastructures and Scientific-Technical Equipment, State Plan for Scientific and Technical Research and Innovation 2017-2020.

Entity: FEDER Program. Spanish Ministry of Science, Innovation and Universities.

Web:  https://sede.micinn.gob.es/stfls/eSede/Ficheros/2019/RPRD_EQC2019_f.pdf

PROJECT: "Study of the application of Neurophotonics, Hyperspectral Imaging and Laser Doppler Vibrometry techniques to improve the neurosurgical treatment of Refractory Surgical Epilepsy".

Program: R&D Health Projects (2016). 

Entity: Regional Ministry of Health, Andalusian Regional Government.​